Synexus HealthyMinds Registry

Alzheimer’s Disease (AD) is on the rise. By joining the Synexus HealthyMinds Registry you will help researchers understand how healthy brains age in order to uncover potential methods of prevention and treatment for Cognitive Decline, AD and other forms of dementia.

Space is limited, so please be that someone who makes a difference and enroll now.

If you are…

  • Aged 50 or older
  • Have access to the Internet
  • Have not been diagnosed with dementia
  • And Live in the United States…

…then you can aid researchers in identifying lifestyle and genetic risk factors that contribute to Cognitive Decline, AD and other forms of dementia.

Participation in the Synexus HealthyMinds Registry is easy, free, and done entirely online. Plus, joining the registry can help you:

  • Stay Sharp

    Free brain-training games exercise the mind and help maintain mental ability

  • Stay Engaged

    Annual cognitive function tests and lifestyle surveys help researchers understand how and why healthy brains change over time

  • Stay Informed

    News on advancements in dementia research and treatment keep you up to date

Join

“We hope to identify ways to prevent and treat dementia so that people can maintain greater independence as they age.”

Dr. Dawie Wessels, Chief Medical Officer of Synexus


“We know dementia risk can be reduced by one-third through improving lifestyle factors from midlife. This study will provide valuable information about how the brain changes with age, which combination of factors such as exercise and diet really work, and how we can best encourage people to adopt these changes.”

Professor Clive Ballard, Executive Dean and Pro-Vice-Chancellor of the University of Exeter Medical School

Join

Target icon

30000

Our target for how many people will take part

Time icon

< 20 hours/year

The time it takes to contribute to dementia research

Age icon

50+

How old you must be to participate in the study

Who can participate?

You can join the study if you:

  • Are aged 50 years or older
  • Have access to the Internet
  • Reside in the United States
  • Do not have a diagnosis of dementia

What is involved?

Once a year, you will be asked to complete a set of questionnaires about yourself, your lifestyle and your health. Each takes an hour or less to complete. You will also be asked to take a series of online tests, to measure changes in brain function.

Examples of Questionnaires, Cognitive Function Tests and Brain Training Games:

Cognitive Function Tasks

Assess core aspects of brain function relevant to everyday activities including attention, memory, reasoning and processing

Brain Training Games

Set of games designed to keep your brain active

Everyday Activities

Please rate yourself on how well you manage your ordinary housework.

Lifestyle

How often do you drink caffeinated drinks (tea, coffee, energy drinks)?

Medical History

Do you regularly experience pain that interferes with your day-to-day life?

Mental Health

People differ a lot in how much they worry about things. Did you ever have a time when you worried a lot more than most would in your situation?

Timeline

Questionnaires
Cognitive Tasks
Repeat annually over 5 years

Brain training games can be played regularly throughout the year

Find out More

What is dementia?

Dementia is a devastating condition that affects the brain. It includes a wide set of symptoms including memory loss, mood changes and problems with communication. It is progressive and there is currently no cure. Research is ongoing to seek better treatments and ways of preventing dementia.

  • Alzheimer’s Disease is the 6th leading cause of death in the United States
  • 16.1 million Americans provide unpaid care for people with Alzheimer’s or other dementias
  • Early and accurate diagnosis could save up to $7.9 trillion in medical and care costs

All figures courtesy of Alzheimer's Association

What is cognitive testing?

The human brain is incredibly complex, performing countless tasks at any one time, allowing us to go about our daily lives. The word “cognitive” is used to describe the brain’s health as it functions. Our mental processes change as we age, and the Synexus HealthyMinds Registry Study is trying to understand and track this process.

The Synexus HealthyMinds Registry Study uses a set of cognitive assessments to record core brain functions including attention, memory, reasoning and processing. Participants are asked to complete tests once a year.

Key Cognitive Processes Assessed by the Synexus HealthyMinds Registry Study

Brain Function What is it? Example of how we test it
Short-term/Working Memory Information is encoded, stored & retrieved You remember where shapes are on a grid or a sequence of numbers
Perception Sensory information like smells, sounds and tastes are recognized and interpreted You recognize a round shape in a grid, interpret it as a football and then perceive it again later
Attention Concentrating on particular information while ignoring other non-related information You demonstrate awareness of a type of object shown in a box and where the box is on a grid but ignore the object’s color
Problem Solving Recognizing a problem and finding the correct answer You work out a rule and apply it to remember where an object appears on a grid
Language Skill to translate sounds into words to communicate with other people You distinguish between words and their location in a sentence to determine the meaning of the sentence

Organizations that provide support for dementia

Our data promise

Your data will be confidential

Your data will be confidential… The study team is committed to safeguarding your personal information


Your data will be securely encrypted

Only a very small number of individuals will have access to the decryption software


Your data will be kept private

Your data will only be used for the purposes of the Synexus HealthyMinds Registry study. See our privacy policy for further information.

The people behind the project

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Professor Clive Ballard

Pro-Vice Chancellor and Executive Dean, University of Exeter Medical School

“We know dementia risk can be reduced by one-third through improving lifestyle factors from midlife. This study will provide valuable information about how the brain changes with age, which combination of factors such as exercise and diet really work, and how we can best encourage people to adopt these changes. This is already proving successful in the U.K., where more than 25,000 people have signed up to help develop better future approaches to prevention and treatment, and we’re delighted to help bring this opportunity to the U.S.”

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Dr. Dawie Wessels

Chief Medical Officer of Synexus

"Synexus HealthyMinds Registry offers participants the opportunity to help society, and potentially themselves and their loved ones, better understand what causes cognitive decline. We hope to identify ways to prevent and treat dementia so that people can maintain greater independence as they age. The registry provides a high level of engagement, pushing out relevant information about the latest advancements in dementia research and treatments, as well as brain-training games designed to help participants stay sharp."

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Dr Anne Corbett

Senior Lecturer in Dementia Research, University of Exeter Medical School

"The internet presents a powerful opportunity for large scale global research that would not have previously been possible. Synexus HealthyMinds Registry will rapidly progress research towards a better understanding of healthy aging and how dementia might be prevented in the future."

Quote from a study participant:

“I'm pleased to say that I found the UK Study very interesting, helpful to understand how memory degrades and affects normal daily life. I was particularly pleased to be able to contribute to this important research which affects millions of people as they age.”

Sign up to hear more

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